Day One of the US Open in New York has a mouthwatering feast of opening round matches, including former world No.1 Andy Murray and Stefanos Tsitsipas meeting for the first time and defending champion Naomi Osaka against Marie Bouzkova in the evening slot on Arthur Ashe Stadium.

Murray says he is looking forward to the challenge of the third-seeded Greek.

“Physically, I’ve been good since I’ve been here in the matches,” Murray said.

Andy Murray in a third round match against Denis Shapovolov at Wimbledon. Photo: Roger Parker International Sports Fotos Ltd

“I pulled up well the following days after them. That for me has been really positive. I would obviously like my game to be in a better place.

“It is interesting sometimes that you don’t feel like you’re playing particularly well, but I’ve had opportunities in my matches against top players in the past few weeks and not quite taken them. Maybe if I did, I’d be sitting here with a slightly different take on things.”

Murray’s last win over a top 20 player was against Alexander Zverev in New York (at the revamped Cincinnati event) a year ago.

Naomi Osaka went out in the last 16 at the Tokyo Olympics.

Osaka should have little difficulty overcoming Czech Bouzkova, but the all-American match of Madison Keys and Sloane Stephens earlier could be the match to watch.

Arya Sabalenka and Daniil Medvedev are also on court, as are with John Isner, Coco Gauff, Garbine Muguruza, Grigor Dimitrov and Nick Kyrgios.

Sabalenka faces Serb Nina Stojanovic on Louis Armstrong in the night session, Medvedev begins his campaign against Frenchman Richard Gasquet, Isner faces fellow American Brandon Nakashima, Gauff Magda Linette from Poland, Muguruza faces Croatian Donna Vekic and Kyrgios has a tough opener against Spaniard Roberto Bautista Agut.

Nick Kyrgios will meet Roberto Bautista Agut in a first round match. Photo: Roger Parker International Sports Fotos Ltd

Arthur Ashe Stadium, Day Session – 12:00 PM Start
Madison Keys (USA) vs. Sloane Stephens (USA)
Andy Murray (GBR) vs. Stefanos Tsitsipas (GRE) [3]

Not Before 7:30 PM
Marie Bouzkova (CZE) vs. Naomi Osaka (JPN) [3]
Richard Gasquet (FRA) vs. Daniil Medvedev (RUS) [2]

Louis Armstrong Stadium, Day Session – 11:00 AM Start
Donna Vekic (CRO) vs. Garbine Muguruza (ESP) [9]
John Isner (USA) [19] vs. Brandon Nakashima (USA) (WC)
Magda Linette (POL) vs. Coco Gauff (USA) [21]

Louis Armstrong Stadium, Night Session – 7:00 PM Start
Nina Stojanovic (SRB) vs. Aryna Sabalenka (BLR) [2]
Roberto Bautista Agut (ESP) [18] vs. Nick Kyrgios (AUS)